Kane, Bellingham and Foden are unable to play together - what's the verdict?
Having secured six victories out of six, zero goals allowed and a World Cup spot secured with two group games to spare, national team coach Thomas Tuchel can argue he has chosen wisely throughout qualification.
Yet, in the build-up to Thursday's home game against Serbia, he sparked a debate when he claimed that three of the nation's top talents - Jude Bellingham, Phil Foden and Harry Kane - cannot play in the identical lineup.
"At the moment, if we maintain the formation, they won't fit together.
"They might but not within this system, not preserving harmony that we developed and not in this formation that also includes wingers who are highly specialized in their positions. We play at the moment with specific numbered positions."
From certain starters to fighting for spots
England's creative talents have been deployed on the flanks for England in the past, but his team selections indicate that Marcus Rashford and the Gunners' star are his preferred options on the wide areas respectively.
But can Bellingham, Foden and Kane play together?
The previous England manager apparently believed they could.
Bellingham, Foden and Kane featured in every England's seven matches at last summer's tournament in Germany, where Southgate's side were defeated by Spain in the final.
In the 16 fixtures the stars have performed together, England have triumphed 10 times, tied three matches and been defeated three times, registering 36 scores and allowing 14 goals.
Analysis: Foden's versatility gives Tuchel options
Tuchel has employed a four-two-three-one setup that changes shape when England attack.
The Aston Villa player has been the main number 10 because of his strong ball-carrying, shooting ability and skill in entering the penalty area when the striker drops deep.
Tuchel has spoken about preferring specialist wingers. The Arsenal and Newcastle stars regularly feature on the wings and can hold the ball well, engage in one-on-one situations, and arrive in the box to score.
Supporting the attacking quartet, Tuchel plays with a midfield two consisting of a disciplined defensive presence and a partner with attacking liberty to support offensive play.
Potential configurations for England's stars
Foden and Bellingham would be vying against other creative midfielders for the number 10 role, with Kane expected to lead up front.
Foden could play as the central striker, which potentially could allow both Bellingham and Foden to play at Kane's expense.
There is an alternative approach all three could play in this system and Tuchel suggested it this week.
"With his club, he plays almost like a central or attacking midfielder, so potentially in future we regard him as a central midfielder," he said.
Foden has been used in a more all-purpose midfield role this season.
That has enabled him to operate from deeper areas and could make him an option as the number eight, paired with a defensive anchor.
This would then permit Bellingham to feature as the attacking midfielder and Kane as the striker.
No matter whether Tuchel decides to set England up like this at the international competition, what seems encouraging is his preparedness to omit established stars in the pursuit of tactical equilibrium.